Description
DNA Damage and Repair: Advances from Phage to Humans provides an in-depth examination of the molecular mechanisms underlying DNA damage recognition and repair pathways. This contemporary cancer research resource traces the evolution of our understanding from studies in bacteriophage systems through to complex human cellular processes.
The book covers essential topics including base excision repair, nucleotide excision repair, mismatch repair, and homologous recombination. Each chapter integrates foundational principles with recent advances, demonstrating how fundamental research in model organisms has illuminated human disease pathways. Particularly valuable for understanding cancer development, the text explores how defects in DNA repair mechanisms contribute to genomic instability and malignant transformation.
Authored by recognized experts in the field, this volume serves as both a comprehensive reference and a current perspective on DNA repair biology. It is essential reading for cancer researchers, molecular biologists, and scientists seeking to understand the cellular mechanisms that maintain genomic integrity and prevent disease.
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