Description
DNA Repair and Human Disease is a definitive scientific resource that examines the intricate relationship between DNA repair processes and the development of human diseases. This hardcover edition, authored by A.S. Balajee and published by the prestigious Springer, offers an in-depth exploration of molecular mechanisms underlying DNA damage recognition, repair pathways, and the consequences of repair deficiencies.
The book covers essential topics including nucleotide excision repair, base excision repair, mismatch repair, and homologous recombination, demonstrating how mutations in DNA repair genes lead to increased cancer susceptibility, premature aging, and neurological disorders. Through detailed case studies and current research findings, readers gain comprehensive understanding of hereditary cancer syndromes such as xeroderma pigmentosum, Lynch syndrome, and BRCA-related cancers.
Ideal for researchers, clinicians, and advanced students in molecular biology, genetics, and oncology, this publication serves as both a reference guide and educational text for understanding the fundamental biology of DNA repair and its clinical implications.
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