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FAS SIGNALING (Medical Intelligence Unit)

SKU: 9780387321721

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FAS Signaling explores the molecular mechanisms and biological significance of Fas-mediated cell death pathways. This comprehensive medical reference provides detailed insights into apoptosis regulation and its clinical implications.

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Description

FAS Signaling is a specialized medical text that examines the Fas/FasL (CD95/CD95L) system, a crucial pathway in programmed cell death and immune regulation. The book provides comprehensive coverage of the molecular mechanisms underlying Fas-mediated apoptosis, including receptor structure, signal transduction cascades, and the role of adapter proteins in cell death execution.

Harald Wajant presents detailed analysis of how Fas signaling regulates immune homeostasis, lymphocyte development, and immune tolerance. The text explores both the beneficial aspects of Fas-induced apoptosis in eliminating autoreactive cells and the pathological consequences when this system malfunctions, including autoimmune diseases and cancer development.

This Medical Intelligence Unit volume synthesizes research on therapeutic applications and potential interventions targeting the Fas pathway. It serves as an essential resource for researchers, clinicians, and students seeking in-depth understanding of apoptotic mechanisms and death receptor signaling in modern medicine.

Additional information

Author

Harald Wajant

Publisher

‏ : ‎ Springer-Verlag New York Inc.

ISBN

9780387321721

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