Explore the future of medicine with “Distributed Diagnosis and Home Healthcare (D2H2)”. This essential book showcases how miniaturized instrumentation, advanced computing, and communication technologies are revolutionizing healthcare. Discover how bio-sensing and information technologies, combined with medical expertise, enable remote diagnosis and personalized care. Part 1 delves into cutting-edge distributed diagnostics, including diabetic foot analysis, plantar pressure classification, and advanced diabetic retinopathy detection from fundus eye images. Part 2 focuses on practical home healthcare solutions, covering rehabilitation, personalized cardiac monitoring, and crucial ethical considerations. Ideal for researchers and practitioners, D2H2 provides a comprehensive overview of biomedical instrumentation, signal processing, medical imaging, and telemedicine, paving the way for next-generation healthcare.