Explore cutting-edge techniques in NUCLEAR REPROGRAMMING: Methods and Protocols, a vital guide for researchers. This Humana Press publication, part of the esteemed Methods in Molecular Biology series, details reproducible methods for nuclear transfer across species, cell fusion via chemical and electrical means, and in vivo reprogramming. It also covers essential monitoring techniques, including transgenic markers, telomerase activation, microscopic analysis, and stem cell differentiation potential. Delve into biochemical protocols for examining chromatin modifications, nucleosomal footprinting, transcription factor binding, and DNA methylation. Essential for anyone in molecular biology seeking to understand or implement nuclear reprogramming.