Explore the latest advancements in understanding Lyme disease with “Lyme Disease: An Evidence-Based Approach.” This comprehensive second edition offers up-to-date research on Lyme borreliosis, covering everything from causative organisms and epidemiology to diagnostic testing and therapeutic options. Delve into host-Borrelia interactions, the impact of host immunity, and long-term prognosis. The book critically examines newly identified borrelial pathogens, molecular biology updates, neuroborreliosis, and diagnostic tools like the C6 peptide. It provides balanced perspectives on complex topics, including controversies surrounding ‘chronic Lyme disease’ and post-Lyme disease syndrome. Essential reading for clinicians, researchers, and students of global health and infectious disease navigating the growing global footprint of Lyme disease.