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The Biochemistry of Drug Metabolism: Volume 2: Conjugations, Consequences of Metabolism, Influencing Factors

SKU: 9783906390543

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Delve into the intricate world of drug metabolism with ‘The Biochemistry of Drug Metabolism: Volume 2: Conjugations, Consequences of Metabolism, Influencing Factors’. This comprehensive guide from The Bookish Owl meticulously details conjugation reactions, including methylation, sulfation, and glucuronidation, alongside xenobiotic-coenzyme A conjugates. Explore the pharmacological and toxicological consequences of metabolism, from prodrug activation to xenobiotic toxification. Understand critical inter-individual and intra-individual factors influencing drug metabolism, such as species differences, genetic polymorphisms, ethnic variations, sex-dependent reactions, enzyme induction, and inhibition. This essential resource covers physiological conditions, pathologies, nutrients, and environmental agents, with a special focus on drug-drug interactions, making it a vital read for professionals and students seeking a deeper understanding of xenobiotic interactions.

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Description

  • ISBN-10: 3906390543
  • ISBN-13: 978-3906390543
  • Edition: 1st
  • Publisher: Wiley-VCH
  • Publication date: 17 March 2010
  • Language: English
  • Dimensions: 17.02 x 3.3 x 23.88 cm
  • Print length: 620 pages